Despite the importance of human blood to clinical practice and research, hematology and blood transfusion data remain scattered throughout a range of disparate sources. This lack of systematization concerning the use and definition of terms poses problems for physicians and biomedical professionals. We are introducing here the Blood Ontology, an ongoing initiative designed to serve as a controlled vocabulary for use in organizing information about blood. The paper describes the scope of the Blood Ontology, its stage of development and some (...) of its anticipated uses. (shrink)

We describe the rationale for an application ontology covering the domain of human body fluids that is designed to facilitate representation, reuse, sharing and integration of diagnostic, physiological, and biochemical data, We briefly review the Blood Ontology (BLO), Saliva Ontology (SALO) and Kidney and Urinary Pathway Ontology (KUPO) initiatives. We discuss the methods employed in each, and address the project of using them as starting point for a unified body fluids ontology resource. We conclude with a description of how the (...) body fluids ontology initiative may provide support to basic and translational science. (shrink)

The historical formation of Brazil is distinguished from the majority of ex-colonial nations by one factor that is especially characteristic: an intense process of ethnic and cultural mixing. The Portuguese colonisers, who, unlike the English Puritans in North America, left their families and arrived in Brazil in small groups mainly composed of men, naturally tended to pair off with the women they found available - first of all indigenous women and later African women. There was nothing in Brazil to prevent (...) this spontaneous behaviour similar to the role played in the English colonies of North America by the strength of the family group or the strict religious observance of the community. Thus from the outset Brazil tended to accept racial mixing as a de facto reality. As Gilberto Freyre correctly noted in his book Casa Grande e Senzala:They mixed happily with women of colour from the very first contacts and many mixed-race children resulted, so much so that only a few thousand men were enough to colonize vast areas and compete with the greatest and most numerous peoples as regards the extent of the colonial territory and the effectiveness of colonizing activity. (shrink)

The historical formation of Brazil is distinguished from the majority of ex-colonial nations by one factor that is especially characteristic: an intense process of ethnic and cultural mixing. The Portuguese colonisers, who, unlike the English Puritans in North America, left their families and arrived in Brazil in small groups mainly composed of men, naturally tended to pair off with the women they found available - first of all indigenous women and later African women. There was nothing in Brazil to prevent (...) this spontaneous behaviour similar to the role played in the English colonies of North America by the strength of the family group or the strict religious observance of the community. Thus from the outset Brazil tended to accept racial mixing as a de facto reality. As Gilberto Freyre correctly noted in his book Casa Grande e Senzala:They mixed happily with women of colour from the very first contacts and many mixed-race children resulted, so much so that only a few thousand men were enough to colonize vast areas and compete with the greatest and most numerous peoples as regards the extent of the colonial territory and the effectiveness of colonizing activity. (shrink)

The institutions we create shape many of the activities we engage insofar as they are pervasive entities in our society. In an era full of new technologies, including the semantic web, there is a movement toward sound conceptual modeling for socio-technical solutions applied to government institutions. To develop these complex solutions, one needs to deepen the ontological status of entities in the institutional domain, because literature is full of ambiguous and ad-hoc hypotheses about distinctions between public and private corporations. We (...) believe we can find better explanations for such distinctions in the interdisciplinary field of library a information science. Within an ongoing semantic web project, we focus on a study case of official documents. First, we analyze theories about public and private corporations, seeking a reliable on‘tological distinction between them; then, by focusing on documents produced by each type of corporation, we hope to provide a well-founded analysis. Second, we adopt the aforementioned theories and the new analysis as recommendations for the improvement for the access and understanding of public documents, through appropriate classification of them within government information systems. This project, ultimately, aims to maximize the transparency of public government documents by favoring retrieval and comprehension by a society with plenty of automated information systems. (shrink)

This paper presents the Obstetric and Neonatal Ontology (OntONeo). This ontology has been created to provide a consensus representation of salient electronic health record (EHR) data and to serve interoperability of the associated data and information systems. More generally, it will serve interoperability of clinical and translational data, for example deriving from genomics disciplines and from clinical trials. Interoperability of EHR data is important to ensuring continuity of care during the prenatal and postnatal periods for both mother and child. As (...) a strategy to advance such interoperability we use an approach based on ontological realism and on the ontology development principles of the Open Biomedical Ontologies Foundry, including reuse of reference ontologies wherever possible. We describe the structure and coverage domain of OntONeo and the process of creating and maintaining the ontology. (shrink)

Electronic health records (EHRs) serve as repositories of documented data collected in a health care encounter. An EHR records information about who receives, who provides the health care and about the place where the encounter happens. We also observe additional elements relating to social relations in which the healthcare consumer is involved. To provide a consensus representation of common data and to enhance interoperability between different EHR repositories we have created a solution grounded in formal ontology. Here, we present how (...) an ontology for the obstetric and neonatal domain deals with these general elements documented in health care encounters. Our goal is to promote the interoperability of information among EHRs created in different specialties. To develop our ontology, we used two main approaches: one based on ontological realism, the other based on the principles of the OBO Foundry, including reuse of reference ontologies. (shrink)

This article provides a state of the art review of the philosophical literature on scientific representation. It first argues that the topic emerges historically mainly out of what may be called the modelling tradition. It then introduces a number of helpful analytical distinctions, and goes on to divide contemporary approaches to scientific representation into two distinct kinds, substantive and deflationary. Analogies with related discussions of artistic representation in aesthetics, and of the nature of truth in metaphysics are pursued. It is (...) finally urged that the most promising approaches - and the ones most likely to feature prominently in future developments - are deflationary. In particular, a defence is provided of a genuinely inferential conception of representation. (shrink)

This article provides a state-of-the-art review of the philosophical literature on scientific representation. It first argues that the topic emerges historically mainly out of what may be called the modelling tradition. It then introduces a number of helpful analytical distinctions and goes on to divide contemporary approaches to scientific representation into two distinct kinds, substantive and deflationary. Analogies with related discussions of artistic representation in aesthetics and the nature of truth in metaphysics are pursued. It is finally urged that the (...) most promising approaches—and the ones most likely to feature prominently in future developments—are deflationary. In particular, a defense is provided of a genuinely inferential conception of representation. (shrink)

O objetivo da pesquisa é apresentar embates e discutir perspectivas sobre a atualidade do conceito de indústria cultural para analisar o uso do smartphone e seus derivados e sua relação com a compreensão leitora e a construção de sentido. A questão que norteia a pesquisa é: Após o término da educação básica e diante do uso constante da linguagem imagética presente nos conteúdos acessados pelos smartphones e seus derivados, é possível o sujeito fazer uma leitura, de forma crítica e dialética (...) de, por exemplo, uma charge? Em que medida, isso poderia ocorrer? A hipótese da pesquisa é que, ao realizar a leitura no aparato, a palavra perde relevância comparada à imagem que é percebida, visualizada, mais do que pensada/entendida e o seu conceito se reduz a uma função icônica. Por isso, o campo semântico se limita a associações automáticas e, dessa forma, operacionalizam-se as leituras. A pesquisa empírica realizada foi desenvolvida com a participação de estudantes com idades entre 17 e 19 anos, ou seja, que já concluíram a educação básica e ingressaram em uma universidade. O instrumento de pesquisa aplicado foi uma questão escrita a partir de uma charge com um assunto vinculado ao dia a dia dos participantes e, uma entrevista previamente formulada. (shrink)

Esta pesquisa fundamenta-se nos debates sobre o papel da escola na atualidade e dos professores em temos de formação, atuação e práticas pedagógicas, dando prioridade nesta abordagem aos novos tempos vivenciados por essa classe de profissionais, pondo em questão as instituições escolares enquanto ambientes formadores e os professores como atores que, muitas vezes, tem papel decisivo para o processo ensino-aprendizagem, papel esse que tem estado em maior evidência por conta das diversas mutações ocorridas na sociedade, caracterizadas pelo mundo contemporâneo. Este (...) estudo está sendo realizado por meio de levantamento bibliográfico. O foco desta investigação determina-se em proporcionar, uma contribuição favorável para discussão sobre a atuação da escola e da prática exercida pelos professores, frente aos novos tempos e aos novos desafios trazidos pela contemporaneidade. (shrink)

On a purely epistemic understanding of experimental realism, manipulation affords a particularly robust kind of causal warrant, which is – like any other warrant – defeasible. I defend a version of Nancy Cartwright’s inference to the most likely cause, and I conclude that this minimally epistemic version of experimental realism is a coherent, adequate and plausible epistemology for science.

Depersonalization is characterised by a profound disruption of self-awareness mainly characterised by feelings of disembodiment and subjective emotional numbing.It has been proposed that depersonalization is caused by a fronto-limbic suppressive mechanism – presumably mediated via attention – which manifests subjectively as emotional numbing, and disables the process by which perception and cognition normally become emotionally coloured, giving rise to a subjective feeling of ‘unreality’.Our functional neuroimaging and psychophysiological studies support the above model and indicate that, compared with normal and clinical (...) controls, DPD patients show increased prefrontal activation as well as reduced activation in insula/limbic-related areas to aversive, arousing emotional stimuli.Although a putative inhibitory mechanism on emotional processing might account for the emotional numbing and characteristic perceptual detachment, it is likely, as suggested by some studies, that parietal mechanisms underpin feelings of disembodiment and lack of agency feelings. (shrink)

In the logic of theory change, the standard model is AGM, proposed by Alchourrón et al. (J Symb Log 50:510–530, 1985 ). This paper focuses on the extension of AGM that accounts for contractions of a theory by a set of sentences instead of only by a single sentence. Hansson (Theoria 55:114–132, 1989 ), Fuhrmann and Hansson (J Logic Lang Inf 3:39–74, 1994 ) generalized Partial Meet Contraction to the case of contractions by (possibly non-singleton) sets of sentences. In this (...) paper we present the possible worlds semantics for partial meet multiple contractions. (shrink)

No presente texto propomos uma perspectiva multiespecífica para a análise da biopolítica. Partindo da situação da emergência da pandemia do COVID-19, tomada dentro do contexto das mutações ecológicas do Antropoceno, argumentamos que, para além da atenção voltada às operações das diversas experiências e dispositivos biopolíticos sobre o corpo humano – corpo individual ou corpo social – deve-se trilhar por uma via expandida que leve também em consideração, conjuntamente (e não por exclusão), os efeitos dessas operações sobre formas de vida outras-que-humanas, (...) tomando termos como meio ambiente e natureza não apenas pelo prisma de serem recursos geridos finalizando a condução da conduta humana, mas como meios vivos, igualmente. (shrink)

1Department of Philosophy, University of Bristol, 9 Woodland Road, Bristol BS8 1TB, UKScience Without Laws Ronald Giere Chicago, IL University of Chicago Press 1999 x + 285 Hardback£17.50.

O trabalho investiga a revista O Clarim, produzida pelos alunos de uma escola, em Porto Alegre/RS, entre os anos de 1945 e 1965. A história de O Clarim constitui-se em uma rica documentação de história da educação, pois revela um pouco das representações da cultura juvenil daquele tempo. Aqui interessam os significados da difusão dos discursos difundidos pelo periódico, nos processos de subjetivação provocados pelos textos e suas possíveis influências na construção das identidades daqueles jovens. A pesquisa identifica-se com os (...) pressupostos teóricos da História Cultural e se inscreve no campo das práticas de leitura e escrita e de memórias juvenis, tendo como referenciais as concepções de cultura escrita como uma produção discursiva de um determinado tempo e lugar. (shrink)

In many countries consumers have shown an increasing interest to the way in which food products are being produced. This study investigates Chinese consumers’ attitudes towards different pig production systems by means of a conjoint analysis. While there has been a range of studies on Western consumers’ attitudes to various forms of food production, little is known about the level of Chinese consumers’ attitudes. A cross-sectional survey was carried out with 472 participants in 6 Chinese cities. Results indicate that Chinese (...) consumers prefer industrial pig production systems, where traditional pig breeds are raised, over large-scale and small family farms. Farms with maximum attention to food safety, which furthermore can provide lean meat with consistent quality, are also preferred. Imported pig breeds and tasty but variable meat were rejected. A 3-cluster solution found that consumers from cluster 1 focus almost exclusively on the food safety aspect (food safety focused). Consumers from cluster 2 (indifferent) show weak overall attitudes to pig production systems in general. Cluster 3 (industrial production oriented) stands out by being very positive about industrial, large-size farms and consistent quality. From a Chinese consumer’s perspective, the industrial approach seems to represent values such as achievement and evolution, as well as quality and safety, since pig production is moving away from low-cost, low-quality, and low-safety family-scale systems. A complex set of rural and environmental development, quality aspects, and food safety measures are challenges that must be met by the stakeholders of pig production systems in China. (shrink)

Maria Isabel Mendes de Almeida mergulhou na tarefa pesada de trabalhar a questão da subjetividade humana, elaborada de maneiras distintas por autores como Rousseau, Tocqueville, Simmel, Weber, Sérgio Buarque de Hollanda, Paulo Prado, Gilberto Freyre e Ant.

The goal of this paper is to assess biological naturalism in light of the adaptationist debate. Searle is famous for explicity pursuing a biological foundation for his theory of consciousness. However, evolutionary biology receives little attention in his work, which results in crucial theoretical confusions over adaptationism. In this paper, we will propose two theses concerning Searle's approach to consciousness in the context of the adaptationist debate. First, Searle's attack on adaptationism only applies to its naive version, failing to touch (...) any of the more sophisticated versions of adaptationism, especially the empirical one. Second, despite his attack, in the end Searle embraces empirical adaptationism about consciousness. Howsoever, Searle's empirical foundation for his thesis that the evolutionary advantage of consciousness lies in a greater power of discrimination faces a serious problem of generalization regarding non-human animals. (shrink)

These are the introduction chapters to the forthcoming collection of essays published by Springer (Synthese Library) and entitled Probabilities, Causes and Propensities in Physics.

On the basis of arguments showing that none of the most influential analyses of Moore's paradox yields a successful resolution of the problem, a new analysis of it is offered. It is argued that, in attempting to render verdicts of either inconsistency or self-contradiction or self-refutation, those analyses have all failed to satisfactorily explain why a Moore-paradoxical proposition is such that it cannot be rationally believed. According to the proposed solution put forward here, a Moore-paradoxical proposition is one for which (...) the believer can have no non-overridden evidence. The arguments for this claim make use of some of Peter Klein's views on epistemic defeasibility. It is further suggested that this proposal may have important meta-epistemological implications. (shrink)

It is still a matter of controversy whether the Principle of the Common Cause (PCC) can be used as a basis for sound causal inference. It is thus to be expected that its application to quantum mechanics should be a correspondingly controversial issue. Indeed the early 90’s saw a flurry of papers addressing just this issue in connection with the EPR correlations. Yet, that debate does not seem to have caught up with the most recent literature on causal inference generally, (...) which has moved on to consider the virtues of a generalised PCC-inspired condition, the so-called Causal Markov Condition (CMC). In this paper we argue that the CMC is an appropriate benchmark for debating possible causal explanations of the EPR correlations. But we go on to take issue with some pronouncements on EPR by defenders of the CMC. (shrink)

IntroductionThe idea of video recording in the operating room with panoramic cameras and microphones is a new concept that is changing the approach to medical activities in the OR. However, VR in the OR has brought up many concerns regarding patient privacy and has highlighted legal and ethical issues that were never previously exposed.AimTo review the literature concerning these aspects and provide a better ethical and legal understanding of the new challenges concerning VR in the OR.ConclusionsThere is a disparity between (...) the two main legal models concerning VR in the OR, namely the European legal system ) and the American legal framework ). This difference mainly deals with two distinct bioethical paradigms: GDPR places a strong emphasis on protecting patients’ privacy to improve the public health system, whereas HIPAA indicates the need to generate protocols to safeguard the risks connected to medical activity and patient privacy. Following from this point, we may argue that, at the ethical and bioethical level, GDPR and HIPAA depend mainly on two different ethical models: a perspective based on moral acquaintances and weak proceduralism, respectively. It is worth noting the importance of developing additional guidelines concerning different world regions to avoid the ethical problems that may emerge when simply applying a foreign paradigm to a very different culture. (shrink)

El modelo de ser humano: homo oeconomicus, impuesto por la racionalidad económica capitalista, ha tenido en las dos últimas décadas una metamorfosis compleja, a saber, la formación de un tipo de subjetividad representada en la figura del “emprendedor” o “su propio jefe” que, desde una nueva gramática teológica, encarna un proyecto mercantil solapado y subrepticio que condiciona las relaciones entre sujetos. En razón a esto, el propósito de este texto es pensar dicha problemática desde el ejercicio hermenéutico-crítico que lleva a (...) cabo el joven Marx, para someter al análisis las categorías de culpa, deuda, sacrificio y expiación destacadas por Walter Benjamin, a la luz de la categoría esencia subjetiva de la propiedad privada que permita entender cómo el capitalismo se vale hoy de la teología y su lenguaje para continuar responsabilizando al ser humano de su pobreza, de su riqueza o su fracaso económico. (shrink)

El objetivo de este artículo es presentar el problema triple (trilema) de Agripa que cuestiona la posibilidad de alcanzar una justificación epistemológica del conocimiento empírico. Una posible reconstrucción del problema es la que se apoya en el problema del regreso al infinito -uno de los modos de..

College students have become more representative as blood donors, mainly to help other people. This study ascertained the association between spirituality and adherence or intention to donate blood in post-graduate students. In this quantitative and cross-sectional study, participants were 281 students from a post-graduate programme at a Brazilian public university. After complying with ethical requirements, data were collected through a questionnaire for sociodemographic characterization and identification of blood donation practices, followed by the Spiritual Well-Being Scale. Descriptive statistics and parametric tests (...) were used for data analysis. A total of 74% of the participants were female and 26% were male. Previous experience and/or intention to donate blood were found in 75.3%; 14.3% donated blood periodically. In addition, 12.2% were not adept to donation and 12.5% were inapt. Spiritual Well-Being scores were similar between individuals who are not adept and those who donate periodically. In conclusion, in the sample, spirituality and blood donation are not associated, but spiritual well-being and gender are. To enhance blood donation, further research is needed. (shrink)

Con el objetivo de superar la crisis en la que se encuentra la filosofía hoy, se expone de manera sencilla una propuesta de una hermenéutica analógica. Se trata de una teoría de la interpretación que incorpora el concepto de la analogía, noción que evitará caer en la postura unívoca de los positivismos y en la equívoca de los posmodernismos. Esto permitirá salir a terrenos más promisorios y fructíferos para la labor filosófica. Para ello, en primer lugar, se desarrollará la concepción (...) de hermenéutica en general y, en segundo lugar, se expondrá el concepto de analogía, de la que toma su nombre la hermenéutica analógica, a fin de que su concepto sea comprendido más fácil y claramente. (shrink)

This paper examines undergraduate business students' perception of corporate social responsibility in cases in which they have not attended any specific course either dealing with CSR or providing training in ethics. A survey was conducted of 535 Spanish business students as future managers. The results show that the stakeholders' perspective deserves a huge attention for those students considering what the keys of business success are. Significant differences in perception were nevertheless identified when a multifactorial analysis was undertaken. Female students are (...) more concerned about CSR issues. The maximization of value for shareholders is less valued by second- and third-year students than by first-year ones. The findings point to a number of important orientations for the future development of university curriculum. (shrink)